Early Detection of Muscle Weakness and Functional Limitations in the Critically Ill: A Retrospective Evaluation of Bioimpedance Spectroscopy

CE Baldwin; K Fetterplace; L Beach; G Kayambu; J Paratz; C Earthman; SM Parry

Journal article

Early Detection of Muscle Weakness and Functional Limitations in the Critically Ill: A Retrospective Evaluation of Bioimpedance Spectroscopy

CE Baldwin, K Fetterplace, L Beach, G Kayambu, J Paratz, C Earthman, SM Parry

Journal of Parenteral and Enteral Nutrition | WILEY | Published : 2020

DOI: 10.1002/jpen.1719

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Abstract

Background: The potential for bioimpedance spectroscopy (BIS) to identify muscle weakness and functional limitations in critical illness is unknown; this study aimed to determine association of BIS with strength/function and differences between 3 intensive care units (ICUs). Methods: A retrospective post hoc analysis of BIS, strength, and functional data from adults who required ≥48 hours of mechanical ventilation was conducted. Measures of body composition included the proportion (%) of total body water (TBW), fat mass (FM), and fat-free mass (FFM). The Medical Research Council sum score (MRC-ss) and Physical Function in ICU Test–Scored (PFIT-s) were used for strength and functional assessm..

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University of Melbourne Researchers

Selina Parry Author

Related Projects (1)

DEMYSTIFYING THE BURDEN OF INTENSIVE CARE SURVIVORSHIP - UNDERSTANDING MUSCLE WASTING AND FALLS

For individuals who survive an intensive care admission, there is no prevention or cure for the development of intensive care acquired weakn..

Grants

Awarded by NHMRC Early Career Fellowship

Awarded by National Health and Medical Research Council of Australia

Funding Acknowledgements

Claire E. Baldwin received funding for consumables as part of the original study from a Flinders Medical Centre Foundation "seeding grant" and maintains a clinical physiotherapy position at the recruitment site, Flinders Medical Centre. Kate Fetterplace received conference, travel grants, and/or honoraria from Baxter, Fresenius Kabi, and Nestle Health Science (not related to this study) and received funding from the Melbourne Health Foundation to undertake the original study. Lisa Beach received funding from the Melbourne Health Foundation to undertake the original study. Geetha Kayambu received funding from the Intensive Care Foundation to undertake the original study. Jennifer Paratz received funding from the Intensive Care Foundation to undertake the original study. Carrie Earthman has received small monetary support and loaner bioimpedance devices from Bodystat LTD, ImpediMed, and InBody. Selina M. Parry is a recipient of an NHMRC Early Career Fellowship (ID: 1111640), which provides protected research time.